Cardiovascular incidence of ischemia and other ischemia related complications

Cardiovascular diseases belong to a category of diseases in which detrimental effects occur on heart and blood vessels. Across the globe , these diseases are the most recurrent cause of human mortality. In India they are believed to account for about a quarter percent of demises. A notable disease affecting the myocardium is myocardial ischemia. In ischemia there is limitation of blood flow in arteries resulting in deficiency of oxygen delivered. The reason behind constraint of blood flow in arteries is plaque hoarding or obstruction due clot appearance. The outcome is the wounding of  myocardial tissue in the state of Ischemic hypoxia.  Various alterations are commenced in the cardiac tissue as a consequence of ischemia.
These involve morphological changes in terms of size of the cardiac tissue, enzymatic changes that pertain to the level and activity of myocardium associated enzymes.
Hemodynamic changes of decline in blood pressure, heart rate and ejection fraction 
are also an aftermath of ischemia.
Arrhythmias some of which are fatal may occur following cases of ischemia.
The net result of these changes is the dysfunctioning of cardiac tissue contributing to heart complications such as heart attack , heart failure , etc
With the current lifestyle trend , incidence of ischemia and other ischemia related complications is on a rise.
Intensive research is being undertaken in hopes of finding cardioprotective agents that have significant reversal effects on ischemia.
Recently , the cardioprotective potential of oxytocin has been identified. 
Oxytocin synthesized in hypothalamus and showing effects of uterine contraction during labor , milk ejection during lactation was also found to be synthesized in heart.
This implies its cardiovascular role.
The delivery of oxytocin to body effects the blood pressure, heart rate, etc..
Oxytocin is found to augment the levels of Atrial Natriuretic Peptide leading to natriuresis which decreases the blood pressure. It also increases nitric  oxide levels causing vasodilation of arteries. These mechanisms culminate in lowering the work load on heart and also elevate the blood supply to ischemic heart.
Hemodynamics changes were recorded in pregnant women administered with oxytocin and undergoing Caesarean section.
The present study tests the hypothesis that oxytocin exerts cardioprotective effects against ischemia.